USAF Air Force SBIR/STTR 2025.4 – Multiple Technology Topics

Air Force technology; aerospace defense; advanced propulsion; directed energy; space systems; technology innovation Technical Requirements: Multiple Air Force technology topics including aerospace defense, advanced propulsion, and space systems Agency: DOD / Air Force Program: SBIR Phase I Topic: USAF-2025.4

Eligibility

Small businesses with fewer than 500 employees.

Small business (< 500 employees)
US-based
For-profit entity
US citizen or permanent resident ownership

Application requirements

1Proposal submission
2SAM.gov registration (UEI required)
3Technical volume
4Cost volume

How to apply

Submit proposal through https://www.sbir.gov/solicitations

Similar opportunities

grant

HHS - SBIR

HHS SBIR FY2026 – Health Technology Innovation (Winter Cycle)

Health technology; biotech; medical innovation; diagnostics; therapeutics; health informatics; research Technical Requirements: HHS SBIR winter cycle topics for health technology innovation and biomedical research Agency: HHS / NIH/CDC/FDA Program: SBIR Phase I Topic: NIH-SBIR-2026-D

$50,000–$275,000Dec 10, 2026

grant

DOD - SBIR

DoD SBIR/STTR FY2026 Release 2 – Batch E

Defense technology; AI; machine learning; autonomy; cybersecurity; technology innovation Technical Requirements: DoD FY2026 Release 2 Batch E covering AI, machine learning, autonomy, and cybersecurity Agency: DOD / Multiple Components Program: SBIR Phase I Topic: FY2026-R2-E

$50,000–$1,800,000Oct 21, 2026

grant

DOD - SBIR

DoD SBIR/STTR FY2026 Release 2 – Batch D

Defense technology; space systems; hypersonics; directed energy; research and development Technical Requirements: DoD FY2026 Release 2 Batch D covering space systems, hypersonics, and directed energy Agency: DOD / Multiple Components Program: SBIR Phase I Topic: FY2026-R2-D

$50,000–$1,800,000Sep 23, 2026

grant

HHS - SBIR

HHS SBIR FY2026 – Biomedical Innovation and Health Research

Biomedical innovation; health research; biotech; therapeutics; medical devices; health technology; research Technical Requirements: HHS SBIR topics for biomedical innovation, health research, and medical device development Agency: HHS / NIH/CDC/FDA Program: SBIR Phase I Topic: NIH-SBIR-2026-C

$50,000–$275,000Sep 6, 2026