NSF SBIR Phase I – Deep Technology Innovation (NSF 26-510) – July 2026 Cycle

Source: sbir.gov Agency: NSF Branch: TIP Directorate Program: SBIR Phase I Topic: NSF-26-510 Research Area: Technology-agnostic deep tech: AI/ML, advanced manufacturing, biotechnology, cybersecurity, quantum, photonics, robotics, environmental technologies Status: open Requirements: High-risk, high-impact deep technology innovations with strong commercial potential. Project Pitch required before full proposal submission.

Eligibility

Small businesses (< 500 employees), US-owned

small_business

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TIP Directorate

NSF SBIR Phase I – Deep Technology Innovation (NSF 26-510) – November 2026 Cycle

Source: sbir.gov Agency: NSF Branch: TIP Directorate Program: SBIR Phase I Topic: NSF-26-510 Research Area: Technology-agnostic deep tech: AI/ML, advanced manufacturing, biotechnology, cybersecurity, quantum, photonics, robotics Status: open Requirements: High-risk, high-impact deep technology innovations. Project Pitch required before full proposal submission.

$305,000Nov 4, 2026

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ARPA-H

ARPA-H SBIR/STTR 2026 – Phase II Technical Pitch (Invited Proposers Only)

Source: sbir.gov Agency: HHS Branch: ARPA-H Program: SBIR Phase II Topic: ARPA-H-2026-SBIR Research Area: Health technology: fertility diagnostics, bioadhesives, toxin removal platforms, endometriosis therapy, autoimmune diagnostics, neurosurgical robotics, ARPA-H lineage technologies Status: open Requirements: Invited proposers only (Solution Summary deadline was July 10, 2026). Seven topic areas: fertility biomarkers, bioadhesives, UNI-PLAT toxin removal, endometriosis therapy, ARPA-H lineage, autoimmune diagnostics, neurosurgical robotics.

$3,500,000Sep 9, 2026

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NIH

NIH STTR Parent Solicitation (PA-27-102) – Clinical Trial Optional – September 2026 Cycle

Source: sbir.gov Agency: HHS Branch: NIH Program: STTR Phase I/II Topic: PA-27-102 Research Area: Biomedical research and health technology innovation with research institution partnership; clinical trial optional Status: open Requirements: Investigator-initiated STTR research within NIH IC mission areas. Requires research institution collaboration. Limit of 9 proposals per fiscal year.

$1,800,000Sep 5, 2026

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NIH

NIH SBIR Parent Solicitation (PA-27-100) – Clinical Trial Optional – September 2026 Cycle

Source: sbir.gov Agency: HHS Branch: NIH Program: SBIR Phase I/II Topic: PA-27-100 Research Area: Biomedical research and health technology innovation across all NIH Institute and Center mission areas; clinical trial optional Status: open Requirements: Investigator-initiated SBIR research within NIH IC mission areas. Limit of 9 proposals per fiscal year. No late submissions accepted.

$1,800,000Sep 5, 2026